Speaker: Jill Stansbury. The synthesis, actions and metabolism of dopamine are described in the first part of the lecture. A description of the effect of dopamine on the endocrine system includes the recent findings of its effects as the key regulatory hormone in the hypothalamus and pituitary. The part St John's wort can play in slowing reuptake of dopamine, thereby increasing circulating levels, is described. The relationship of dopamine to the neuropeptides, to fat metabolism and to brain function are also included in this comprehensive presentation.