20ME14 - Neuroplasticity and the NMDA Receptor: Botanical and Nutritional Influences on Neurological Remodeling

Speaker: Kenneth Proefrock, ND Experience-dependent plasticity is a fundamental property of the brain and our nervous systems are constantly remodeling, but such remodeling can be impaired in a wide range of neurological and psychiatric disorders. Several clinical studies suggest that augmenting or reducing NMDA receptor signaling can have a significant impact on experience-dependent plasticity. Augmenting NMDA activity has the effect of improving cognition and mental processing, blunting NMDA activity has been shown to reduce PTSD episodes, anxiety and the frequency and severity of seizure activity. We discuss the neurotransmitter actions of glutamate, aspartate, glycine and serine on the NMDA receptor as well as the impact of NMDA agonists like Tabernanthe iboga, and take a look at some of the more recent pharmaceutical interventions that have been instrumental in informing our current perspective on NMDA activity. Catalog Number 20ME14

Related product: The Lecture Notes and PowerPoint for this recording are available here: 2020 Medicines from the Earth Herb Symposium: Conference Book Download (PDF)