Esophageal reflux, commonly known as gastroesophageal reflux disease (GERD), is a chronic condition where stomach contents flow back into the esophagus, causing symptoms like heartburn, regurgitation and, in severe cases, damage to the esophageal lining. Conventional treatment options, including proton pump inhibitors (PPIs) and H2 receptor antagonists, focus on reducing stomach acid production to alleviate symptoms and prevent complications. However, prolonged use of these medications is associated with potential side effects, such as impaired nutrient absorption, an increased risk of fractures, chronic kidney disease and changes in gut microbiota, prompting many patients to consider alternative management options.